Our delicious Meatloaf Sandwich recipe includes a thick slice of meatloaf topped with melted cheese, crisp spinach, and tangy sauce sandwiched between toasted bread.

Don’t miss my other awesome sandwiches including this Pimento Cheese BLT, Cuban Sandwich, Banh Mi sandwich, and Monte Cristo Sandwich!

A cold meatloaf sandwich topped with sauce, melted cheese, and spinach on a toasty ciabatta roll.

Why I love this sandwich:

  • Easy – I can’t think of a better way to use up leftover meatloaf. Transform last night’s meal into a completely new one in just 15 minutes.
  • Versatile – The topping options are endless here, so pile it with whatever you love and serve it hot or cold. We enjoy it best hot, on toasted bread with the meatloaf and cheese broiled until warm and melted.
All of the ingredients for a leftover meatloaf sandwich recipe: meatloaf, ciabatta rolls, cheese, spinach, and the ingredients for a simple meatloaf sauce.

How to make a Meatloaf Sandwich:

Make Sauce by mixing together all sauce ingredients. Store in the fridge for up to several days.

Assemble: Spread a layer of sauce over the bottom half of bread. Top with a slice of meatloaf and a slice of cheese.

A classic meatloaf sandwich assembled and topped with a slice of cheese, ready to be broiled.

Broil: Place on a baking tray with the tops of the bread up and broil until cheese is melted and bread is toasted. Add a handful of spinach on the melted cheese, then top with toasted top layer of bread. Serve the best meatloaf sandwich with extra sauce on the side, for dipping.

The best Meatloaf Sandwich, toasty and dripping with a tangy sauce.

Make Ahead and Freezing Instructions:

To Make Ahead: Use leftover meatloaf or to make with fresh meatloaf, shape meatloaf in pan 1-2 days ahead of time. Cover and store in the refrigerator until ready to bake.

To Freeze: Cut baked meatloaf into slices and allow to cool completely. Flash freeze slices on a baking sheet for one hour until semi frozen, then place in a freezer bag and freeze for up to 3 months. 

Recipe Variations:

  • Fried Meatloaf Sandwich: Heat a skillet with ¼ inch oil, until oil is hot. Add one egg and a splash of milk to a shallow bowl and beat well until smooth. Add ½ cup flour and ½ teaspoon each of salt, pepper, paprika and baking powder to another shallow bowl. Dip the cold slices of meatloaf in beaten egg mixture, then flour. Fry for a few minutes on each side, until golden. Assemble classic meatloaf sandwich as directed.
  • Bread: Use a tortilla to make a meatloaf wrap, or serve in a lettuce wrap for a low-carb option.
  • Toppings: Try adding leftover mashed potatoes, pickles, jalapeños, sautéed onions or mushrooms, crispy onion straws, bacon, lettuce, tomato.

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Recipe

Meatloaf Sandwich thumbnail image.
Prep 10 minutes
Cook 5 minutes
Total 15 minutes
Save Recipe

Ingredients
 
 

  • 8 Artisan bread rolls* , like ciabatta or torta
  • 3 Tablespoon butter
  • 8 slices cheese , cheddar, provolone, or Swiss
  • 1 cup baby spinach leaves*
  • 1 recipe cooked leftover Meatloaf , sliced at least 1 inch thick

For the Meatloaf Sauce:

Instructions
 

  • Turn oven to high Broil.
  • Make the meatloaf sauce by mixing together the sauce ingredients.
  • Butter both insides of the bread roll and place in oven to toast. Remove from oven when edges begin to get golden and then spread a generous layer of meatloaf sauce over the bottom half of bread. Top with a slice of meatloaf and a slice of cheese. Return to oven until cheese is melted.
  • Add a handful of spinach and place the top layer of bread. Serve with extra sauce for dipping, if desired.

Notes

Bread: Use a tortilla to make a meatloaf wrap, or serve in a lettuce wrap for a low-carb option.
Toppings: Try adding leftover mashed potatoes, pickles, jalapeños, sautéed onions or mushrooms, crispy onion straws, bacon, lettuce, tomato.
Make Ahead Instructions: Use leftover meatloaf or to make with fresh meatloaf, shape meatloaf in pan 1-2 days ahead of time. Cover and store in the refrigerator until ready to bake.
Freezing Instructions: Cut baked meatloaf into slices and allow to cool completely. Flash freeze slices on a baking sheet for one hour until semi frozen, then place in a freezer bag and freeze for up to 3 months. 
Fried Meatloaf Sandwich: Heat a skillet with ¼ inch oil, until oil is hot. Add one egg and a splash of milk to a shallow bowl and beat well until smooth. Add ½ cup flour and ½ teaspoon each of salt, pepper, paprika and baking powder to another shallow bowl. Dip the cold slices of meatloaf in beaten egg mixture, then flour. Fry for a few minutes on each side, until golden. Assemble classic meatloaf sandwich as directed.

Nutrition

Calories: 220kcalCarbohydrates: 39gProtein: 5gFat: 5gSaturated Fat: 3gPolyunsaturated Fat: 0.2gMonounsaturated Fat: 1gTrans Fat: 0.2gCholesterol: 12mgSodium: 475mgPotassium: 79mgFiber: 1gSugar: 12gVitamin A: 565IUVitamin C: 2mgCalcium: 21mgIron: 0.3mg

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I originally shared this recipe February 2021. Updated February 2024.

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About The Author

Lauren Allen

Welcome! I’m Lauren, a mom of four and lover of good food. Here you’ll find easy recipes and weeknight meal ideas made with real ingredients, with step-by-step photos and videos.

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  1. 5 stars
    The absolute BEST sandwich EVER! We made your meatloaf for Sunday dinner and had leftovers and remember seeing this while looking at the meatloaf recipe. What a perfect way to use leftovers. The sauce was fantastic!